What Does Mounjaro Do to Your Gut? The Complete Guide

GLP-1 medications like Mounjaro (tirzepatide) slow down gastric emptying. This can lead to constipation, bloating, and intestinal discomfort. In this article, we explain what exactly happens in your intestines and how you can support them.

How GLP-1 affects your digestion

Tirzepatide slows down gastric emptying by an average of 30-40%. This leads to a longer feeling of fullness, but also to slower transit in the intestines.

What helps?

Psyllium fibers gently support bowel movement. Akkermansia muciniphila supports gut wall integrity and the microbiome. Both are included in Mayntain Daily.

Practical tips

  • Drink at least 2 liters of water per day
  • Exercise daily; even a short walk helps
  • Take psyllium fiber daily, preferably in the morning

Dealing with queasiness too? Read our guide on nausea on Mounjaro and what helps.

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